Aging is associated with highly reproducible DNA-methylation changes at specific sites in the genome. Cygenia provides methods to estimate “biological age” based on specific genomic regions.
Cells in culture maintain epigenetic characteristics of their tissue of origin, their cell type, differentiation potential, and culture conditions. Cygenia provides methods for quality control of cell preparations and to estimate the cellular composition.
Particularly malignant diseases are associated with specific changes in the DNA-methylation pattern. Cygenia can provide serive for research to develop biomarkers that may be of prognostic relevance.
Cygenia provides service for for experimental design on epigenetic analysis and DNA methylation profiling.