Epigenetic-Aging-Signature for Blood

Biological aging is reflected by highly reproducible DNA-methylation changes at specific sites in the genome. Biological age can be estimated based on DNA-methylation levels at three specific CpG sides in blood samples.

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Epigenetic-Aging-Signature for Buccal Swabs

Alternatively, genomic DNA can be harvested non-invasively from the inside of a person's cheek with buccal swabs. Cygenia provides new models to estimate biological age with buccal swabs. The precision of age predictions is further increased with a Buccal-Cell-Signature which estimates the percentage of buccal epithelial cells versus leukocytes.

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Epigenetic Aging in Mice

Mice are often used for intervention studies to determine how treatment or specific genetic background impact on biological aging. Cygenia provides a new epigenetic signature to estimate the biological age of mice.

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