Epigenetic-Aging-Signature for Blood
Biological aging is reflected by highly reproducible DNA-methylation changes at specific sites in the genome. Biological age can be estimated based on DNA-methylation levels at three specific CpG sides in blood samples.
Epigenetic-Aging-Signature for Buccal Swabs
Alternatively, genomic DNA can be harvested non-invasively from the inside of a person's cheek with buccal swabs. Cygenia provides new models to estimate biological age with buccal swabs. The precision of age predictions is further increased with a Buccal-Cell-Signature which estimates the percentage of buccal epithelial cells versus leukocytes.